{
  "resourceType" : "Bundle",
  "id" : "300-multiitem-prescription-with-orchestration",
  "type" : "collection",
  "entry" : [{
    "fullUrl" : "https://example.com/RequestOrchestration/300-RequestOrchestration",
    "resource" : {
      "resourceType" : "RequestOrchestration",
      "id" : "300-RequestOrchestration",
      "text" : {
        "status" : "generated",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"RequestOrchestration_300-RequestOrchestration\"> </a><p class=\"res-header-id\"><b>Generated Narrative: RequestOrchestration 300-RequestOrchestration</b></p><a name=\"300-RequestOrchestration\"> </a><a name=\"hc300-RequestOrchestration\"> </a><a name=\"300-RequestOrchestration-en-US\"> </a><p><b>groupIdentifier</b>: 300</p><p><b>status</b>: Active</p><p><b>intent</b>: Order</p><p><b>subject</b>: <a href=\"Patient-patient1.html\">Thomas Engine  Male, DoB: 1950-09-15 ( 12345)</a></p><blockquote><p><b>action</b></p><p><b>resource</b>: <a href=\"MedicationRequest-300-2-medication-prescription-request1.html\">MedicationRequest: identifier = 300-1/2; groupIdentifier = 300; status = active; intent = order; authoredOn = 2024-10-06</a></p></blockquote><blockquote><p><b>action</b></p><p><b>resource</b>: <a href=\"MedicationRequest-300-2-medication-prescription-request2.html\">MedicationRequest: identifier = 300-2/2; groupIdentifier = 300; status = active; intent = order; authoredOn = 2024-10-06</a></p></blockquote></div>"
      },
      "groupIdentifier" : {
        "value" : "300"
      },
      "status" : "active",
      "intent" : "order",
      "subject" : {
        "reference" : "Patient/patient1"
      },
      "action" : [{
        "resource" : {
          "reference" : "MedicationRequest/300-2-medication-prescription-request1"
        }
      },
      {
        "resource" : {
          "reference" : "MedicationRequest/300-2-medication-prescription-request2"
        }
      }]
    }
  },
  {
    "fullUrl" : "https://example.com/MedicationRequest/300-2-medication-prescription-request1",
    "resource" : {
      "resourceType" : "MedicationRequest",
      "id" : "300-2-medication-prescription-request1",
      "meta" : {
        "profile" : ["http://profiles.ihe.net/PHARM/MPD/StructureDefinition/IHEMedicationPrescription"]
      },
      "text" : {
        "status" : "generated",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"MedicationRequest_300-2-medication-prescription-request1\"> </a><p class=\"res-header-id\"><b>Generated Narrative: MedicationRequest 300-2-medication-prescription-request1</b></p><a name=\"300-2-medication-prescription-request1\"> </a><a name=\"hc300-2-medication-prescription-request1\"> </a><a name=\"300-2-medication-prescription-request1-en-US\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-IHEMedicationPrescription.html\">IHE Medication Prescription</a></p></div><p><b>identifier</b>: 300-1/2</p><p><b>groupIdentifier</b>: 300</p><p><b>status</b>: Active</p><p><b>intent</b>: Order</p><h3>Medications</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Reference</b></td></tr><tr><td style=\"display: none\">*</td><td><a href=\"Medication-02A2-CanifugCremolumPessaryItem.html\">Medication: extension = Pessary; doseForm = Pessary; totalVolume = 6 Pessary</a></td></tr></table><p><b>subject</b>: <a href=\"Patient-patient1.html\">Thomas Engine  Male, DoB: 1950-09-15 ( 12345)</a></p><p><b>authoredOn</b>: 2024-10-06</p><p><b>requester</b>: <a href=\"PractitionerRole-doctor1.html\">PractitionerRole Clinical oncologist</a></p><h3>Reasons</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Concept</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://snomed.info/sct 72934000}\">Candidiasis of vagina</span></td></tr></table><blockquote><p><b>dosageInstruction</b></p><p><b>timing</b>: Late Evening, Once per 1 day</p><h3>DoseAndRates</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Dose[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>1 Pessary<span style=\"background: LightGoldenRodYellow\"> (Details: SNOMED CT  code733007009 = 'Pessary (unit of presentation)')</span></td></tr></table></blockquote><h3>DispenseRequests</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>ValidityPeriod</b></td><td><b>NumberOfRepeatsAllowed</b></td><td><b>Quantity</b></td></tr><tr><td style=\"display: none\">*</td><td>2024-10-06 --&gt; 2024-12-06</td><td>1</td><td>6 Pessary<span style=\"background: LightGoldenRodYellow\"> (Details: SNOMED CT  code733007009 = 'Pessary (unit of presentation)')</span></td></tr></table></div>"
      },
      "identifier" : [{
        "value" : "300-1/2"
      }],
      "groupIdentifier" : {
        "value" : "300"
      },
      "status" : "active",
      "intent" : "order",
      "medication" : {
        "reference" : {
          "reference" : "Medication/02A2-CanifugCremolumPessaryItem"
        }
      },
      "subject" : {
        "reference" : "Patient/patient1"
      },
      "authoredOn" : "2024-10-06",
      "requester" : {
        "reference" : "PractitionerRole/doctor1"
      },
      "reason" : [{
        "concept" : {
          "coding" : [{
            "system" : "http://snomed.info/sct",
            "code" : "72934000",
            "display" : "Candidiasis of vagina"
          }]
        }
      }],
      "dosageInstruction" : [{
        "timing" : {
          "repeat" : {
            "boundsDuration" : {
              "value" : 6,
              "unit" : "day",
              "system" : "http://unitsofmeasure.org",
              "code" : "d"
            },
            "frequency" : 1,
            "period" : 1,
            "periodUnit" : "d",
            "when" : ["EVE.late"]
          }
        },
        "doseAndRate" : [{
          "doseQuantity" : {
            "value" : 1,
            "unit" : "Pessary",
            "system" : "http://snomed.info/sct",
            "code" : "733007009"
          }
        }]
      }],
      "dispenseRequest" : {
        "validityPeriod" : {
          "start" : "2024-10-06",
          "end" : "2024-12-06"
        },
        "numberOfRepeatsAllowed" : 1,
        "quantity" : {
          "value" : 6,
          "unit" : "Pessary",
          "system" : "http://snomed.info/sct",
          "code" : "733007009"
        }
      }
    }
  },
  {
    "fullUrl" : "https://example.com/MedicationRequest/300-2-medication-prescription-request2",
    "resource" : {
      "resourceType" : "MedicationRequest",
      "id" : "300-2-medication-prescription-request2",
      "meta" : {
        "profile" : ["http://profiles.ihe.net/PHARM/MPD/StructureDefinition/IHEMedicationPrescription"]
      },
      "text" : {
        "status" : "generated",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"MedicationRequest_300-2-medication-prescription-request2\"> </a><p class=\"res-header-id\"><b>Generated Narrative: MedicationRequest 300-2-medication-prescription-request2</b></p><a name=\"300-2-medication-prescription-request2\"> </a><a name=\"hc300-2-medication-prescription-request2\"> </a><a name=\"300-2-medication-prescription-request2-en-US\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-IHEMedicationPrescription.html\">IHE Medication Prescription</a></p></div><p><b>identifier</b>: 300-2/2</p><p><b>groupIdentifier</b>: 300</p><p><b>status</b>: Active</p><p><b>intent</b>: Order</p><h3>Medications</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Reference</b></td></tr><tr><td style=\"display: none\">*</td><td><a href=\"Medication-02A1-CanifugCremolumCreamItem.html\">Medication: extension = Tube,20 gram; doseForm = Vaginal cream; totalVolume = 1 Tube</a></td></tr></table><p><b>subject</b>: <a href=\"Patient-patient1.html\">Thomas Engine  Male, DoB: 1950-09-15 ( 12345)</a></p><p><b>authoredOn</b>: 2024-10-06</p><p><b>requester</b>: <a href=\"PractitionerRole-doctor1.html\">PractitionerRole Clinical oncologist</a></p><h3>Reasons</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Concept</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://snomed.info/sct 72934000}\">Candidiasis of vagina</span></td></tr></table><blockquote><p><b>dosageInstruction</b></p><p><b>timing</b>: 2 per 1 day</p><h3>DoseAndRates</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Dose[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>1 Application - unit of product usage<span style=\"background: LightGoldenRodYellow\"> (Details: SNOMED CT  code413568008 = 'Application')</span></td></tr></table></blockquote><h3>DispenseRequests</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>ValidityPeriod</b></td><td><b>NumberOfRepeatsAllowed</b></td><td><b>Quantity</b></td></tr><tr><td style=\"display: none\">*</td><td>2024-10-06 --&gt; 2024-12-06</td><td>1</td><td>20 gram(s)<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  codeg = 'g')</span></td></tr></table></div>"
      },
      "identifier" : [{
        "value" : "300-2/2"
      }],
      "groupIdentifier" : {
        "value" : "300"
      },
      "status" : "active",
      "intent" : "order",
      "medication" : {
        "reference" : {
          "reference" : "Medication/02A1-CanifugCremolumCreamItem"
        }
      },
      "subject" : {
        "reference" : "Patient/patient1"
      },
      "authoredOn" : "2024-10-06",
      "requester" : {
        "reference" : "PractitionerRole/doctor1"
      },
      "reason" : [{
        "concept" : {
          "coding" : [{
            "system" : "http://snomed.info/sct",
            "code" : "72934000",
            "display" : "Candidiasis of vagina"
          }]
        }
      }],
      "dosageInstruction" : [{
        "timing" : {
          "repeat" : {
            "boundsDuration" : {
              "value" : 6,
              "unit" : "day",
              "system" : "http://unitsofmeasure.org",
              "code" : "d"
            },
            "frequency" : 2,
            "period" : 1,
            "periodUnit" : "d"
          }
        },
        "doseAndRate" : [{
          "doseQuantity" : {
            "value" : 1,
            "unit" : "Application - unit of product usage",
            "system" : "http://snomed.info/sct",
            "code" : "413568008"
          }
        }]
      }],
      "dispenseRequest" : {
        "validityPeriod" : {
          "start" : "2024-10-06",
          "end" : "2024-12-06"
        },
        "numberOfRepeatsAllowed" : 1,
        "quantity" : {
          "value" : 20,
          "unit" : "gram(s)",
          "system" : "http://unitsofmeasure.org",
          "code" : "g"
        }
      }
    }
  },
  {
    "fullUrl" : "https://example.com/PractitionerRole/doctor1",
    "resource" : {
      "resourceType" : "PractitionerRole",
      "id" : "doctor1",
      "text" : {
        "status" : "generated",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"PractitionerRole_doctor1\"> </a><p class=\"res-header-id\"><b>Generated Narrative: PractitionerRole doctor1</b></p><a name=\"doctor1\"> </a><a name=\"hcdoctor1\"> </a><a name=\"doctor1-en-US\"> </a><p><b>practitioner</b>: <a href=\"Practitioner-practitioner1.html\">Dr Meryl Ärztin</a></p><p><b>organization</b>: <a href=\"Organization-organization1.html\">Dr Ärztin Private Practice</a></p><p><b>code</b>: <span title=\"Codes:{http://snomed.info/sct 309295000}\">Clinical oncologist</span></p></div>"
      },
      "practitioner" : {
        "reference" : "Practitioner/practitioner1",
        "display" : "Dr Meryl Ärztin"
      },
      "organization" : {
        "reference" : "Organization/organization1",
        "display" : "Dr Ärztin Private Practice"
      },
      "code" : [{
        "coding" : [{
          "system" : "http://snomed.info/sct",
          "code" : "309295000",
          "display" : "Clinical oncologist"
        }]
      }]
    }
  },
  {
    "fullUrl" : "https://example.com/Patient/patient1",
    "resource" : {
      "resourceType" : "Patient",
      "id" : "patient1",
      "text" : {
        "status" : "generated",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Patient_patient1\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Patient patient1</b></p><a name=\"patient1\"> </a><a name=\"hcpatient1\"> </a><a name=\"patient1-en-US\"> </a><p style=\"border: 1px #661aff solid; background-color: #e6e6ff; padding: 10px;\">Thomas Engine  Male, DoB: 1950-09-15 ( 12345)</p><hr/></div>"
      },
      "identifier" : [{
        "value" : "12345"
      }],
      "name" : [{
        "family" : "Engine",
        "given" : ["Thomas"]
      }],
      "gender" : "male",
      "birthDate" : "1950-09-15"
    }
  },
  {
    "fullUrl" : "https://example.com/Medication/02A2-CanifugCremolumPessaryItem",
    "resource" : {
      "resourceType" : "Medication",
      "id" : "02A2-CanifugCremolumPessaryItem",
      "meta" : {
        "profile" : ["http://profiles.ihe.net/PHARM/MPD/StructureDefinition/IHEMedication"]
      },
      "text" : {
        "status" : "extensions",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Medication_02A2-CanifugCremolumPessaryItem\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Medication 02A2-CanifugCremolumPessaryItem</b></p><a name=\"02A2-CanifugCremolumPessaryItem\"> </a><a name=\"hc02A2-CanifugCremolumPessaryItem\"> </a><a name=\"02A2-CanifugCremolumPessaryItem-en-US\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-IHEMedication.html\">IHE Medication</a></p></div><p><b>Medication - Unit of presentation</b>: <span title=\"Codes:{http://standardterms.edqm.eu 15039000}\">Pessary</span></p><p><b>doseForm</b>: <span title=\"Codes:{http://standardterms.edqm.eu 10909000}\">Pessary</span></p><p><b>totalVolume</b>: 6 Pessary<span style=\"background: LightGoldenRodYellow\"> (Details: standardterms.edqm.eu  code15039000 = 'Pessary')</span></p><blockquote><p><b>ingredient</b></p><h3>Items</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Concept</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://snomed.info/sct 387325003}\">Clotrimazole</span></td></tr></table><p><b>isActive</b>: true</p><p><b>strength</b>: 100 milligram<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  codemg = 'mg')</span>/1 Pessary<span style=\"background: LightGoldenRodYellow\"> (Details: standardterms.edqm.eu  code15039000 = 'Pessary')</span></p></blockquote></div>"
      },
      "extension" : [{
        "url" : "http://profiles.ihe.net/PHARM/MPD/StructureDefinition/ihe-ext-medication-unitofpresentation",
        "valueCodeableConcept" : {
          "coding" : [{
            "system" : "http://standardterms.edqm.eu",
            "code" : "15039000",
            "display" : "Pessary"
          }]
        }
      }],
      "doseForm" : {
        "coding" : [{
          "system" : "http://standardterms.edqm.eu",
          "code" : "10909000",
          "display" : "Pessary"
        }]
      },
      "totalVolume" : {
        "value" : 6,
        "unit" : "Pessary",
        "system" : "http://standardterms.edqm.eu",
        "code" : "15039000"
      },
      "ingredient" : [{
        "item" : {
          "concept" : {
            "coding" : [{
              "system" : "http://snomed.info/sct",
              "code" : "387325003",
              "display" : "Clotrimazole"
            }]
          }
        },
        "isActive" : true,
        "strengthRatio" : {
          "numerator" : {
            "value" : 100,
            "unit" : "milligram",
            "system" : "http://unitsofmeasure.org",
            "code" : "mg"
          },
          "denominator" : {
            "value" : 1,
            "unit" : "Pessary",
            "system" : "http://standardterms.edqm.eu",
            "code" : "15039000"
          }
        }
      }]
    }
  },
  {
    "fullUrl" : "https://example.com/Medication/02A1-CanifugCremolumCreamItem",
    "resource" : {
      "resourceType" : "Medication",
      "id" : "02A1-CanifugCremolumCreamItem",
      "meta" : {
        "profile" : ["http://profiles.ihe.net/PHARM/MPD/StructureDefinition/IHEMedication"]
      },
      "text" : {
        "status" : "extensions",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Medication_02A1-CanifugCremolumCreamItem\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Medication 02A1-CanifugCremolumCreamItem</b></p><a name=\"02A1-CanifugCremolumCreamItem\"> </a><a name=\"hc02A1-CanifugCremolumCreamItem\"> </a><a name=\"02A1-CanifugCremolumCreamItem-en-US\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-IHEMedication.html\">IHE Medication</a></p></div><p><b>Medication - Unit of presentation</b>: <span title=\"Codes:{http://standardterms.edqm.eu 15058000}\">Tube</span></p><p><b>Medication - Size of Item</b>: 20 gram<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  codeg = 'g')</span></p><p><b>doseForm</b>: <span title=\"Codes:{http://standardterms.edqm.eu 10901000}\">Vaginal cream</span></p><p><b>totalVolume</b>: 1 Tube<span style=\"background: LightGoldenRodYellow\"> (Details: standardterms.edqm.eu  code15058000 = 'Tube')</span></p><blockquote><p><b>ingredient</b></p><h3>Items</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Concept</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://snomed.info/sct 387325003}\">Clotrimazole</span></td></tr></table><p><b>isActive</b>: true</p><p><b>strength</b>: 10 milligram<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  codemg = 'mg')</span>/1 gram<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  codeg = 'g')</span></p></blockquote></div>"
      },
      "extension" : [{
        "url" : "http://profiles.ihe.net/PHARM/MPD/StructureDefinition/ihe-ext-medication-unitofpresentation",
        "valueCodeableConcept" : {
          "coding" : [{
            "system" : "http://standardterms.edqm.eu",
            "code" : "15058000",
            "display" : "Tube"
          }]
        }
      },
      {
        "url" : "http://profiles.ihe.net/PHARM/MPD/StructureDefinition/ihe-ext-medication-sizeofitem",
        "valueQuantity" : {
          "value" : 20,
          "unit" : "gram",
          "system" : "http://unitsofmeasure.org",
          "code" : "g"
        }
      }],
      "doseForm" : {
        "coding" : [{
          "system" : "http://standardterms.edqm.eu",
          "code" : "10901000",
          "display" : "Vaginal cream"
        }]
      },
      "totalVolume" : {
        "value" : 1,
        "unit" : "Tube",
        "system" : "http://standardterms.edqm.eu",
        "code" : "15058000"
      },
      "ingredient" : [{
        "item" : {
          "concept" : {
            "coding" : [{
              "system" : "http://snomed.info/sct",
              "code" : "387325003",
              "display" : "Clotrimazole"
            }]
          }
        },
        "isActive" : true,
        "strengthRatio" : {
          "numerator" : {
            "value" : 10,
            "unit" : "milligram",
            "system" : "http://unitsofmeasure.org",
            "code" : "mg"
          },
          "denominator" : {
            "value" : 1,
            "unit" : "gram",
            "system" : "http://unitsofmeasure.org",
            "code" : "g"
          }
        }
      }]
    }
  }]
}